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Peculiar purulence: Hypervirulent Klebsiella pneumoniae causing pyomyositis

This report describes the first confirmed case of isolated pyomyositis caused by a hypervirulent strain of Klebsiella pneumoniae. Pyomyositis is almost universally caused by gram-positive organisms and while the recent emergence of invasive disease due to hypervirulent K. pneumoniae has been well do...

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Detalles Bibliográficos
Autores principales: Mgbemena, Okechukwu, Serota, David P., Kumar, Sonali, Wozniak, Jessie E., Weiss, David S., Kempker, Russell Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994752/
https://www.ncbi.nlm.nih.gov/pubmed/29030138
http://dx.doi.org/10.1016/j.ijid.2017.09.030
Descripción
Sumario:This report describes the first confirmed case of isolated pyomyositis caused by a hypervirulent strain of Klebsiella pneumoniae. Pyomyositis is almost universally caused by gram-positive organisms and while the recent emergence of invasive disease due to hypervirulent K. pneumoniae has been well documented, the most common clinical manifestation reported is liver abscess. The K. pneumoniae isolate in our case had a hypermucousviscous phenotype as demonstrated by a positive string test and was confirmed to be hypervirulent with molecular testing. Documenting the extrahepatic manifestations of hypervirulent Klebsiella pneumoniae strains is important to increase clinical awareness and in guiding empiric antibiotic regimens.