Cargando…
Guiding Management in Severe Trauma: Reviewing Factors Predicting Outcome in Vastly Injured Patients
Trauma is one of the leading causes of death worldwide, with road traffic collisions, suicides, and homicides accounting for the majority of injury-related deaths. Since trauma mainly affects young age groups, it is recognized as a serious social and economic threat, as annually, almost 16,000 postt...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994855/ https://www.ncbi.nlm.nih.gov/pubmed/29937635 http://dx.doi.org/10.4103/JETS.JETS_74_17 |
_version_ | 1783330519423909888 |
---|---|
author | Lilitsis, Emmanuel Xenaki, Sofia Athanasakis, Elias Papadakis, Eleftherios Syrogianni, Pavlina Chalkiadakis, George Chrysos, Emmanuel |
author_facet | Lilitsis, Emmanuel Xenaki, Sofia Athanasakis, Elias Papadakis, Eleftherios Syrogianni, Pavlina Chalkiadakis, George Chrysos, Emmanuel |
author_sort | Lilitsis, Emmanuel |
collection | PubMed |
description | Trauma is one of the leading causes of death worldwide, with road traffic collisions, suicides, and homicides accounting for the majority of injury-related deaths. Since trauma mainly affects young age groups, it is recognized as a serious social and economic threat, as annually, almost 16,000 posttrauma individuals are expected to lose their lives and many more to end up disabled. The purpose of this research is to summarize current knowledge on factors predicting outcome – specifically mortality risk – in severely injured patients. Development of this review was mainly based on the systematic search of PubMed medical library, Cochrane database, and advanced trauma life support Guiding Manuals. The research was based on publications between 1994 and 2016. Although hypovolemic, obstructive, cardiogenic, and septic shock can all be seen in multi-trauma patients, hemorrhage-induced shock is by far the most common cause of shock. In this review, we summarize current knowledge on factors predicting outcome – more specifically mortality risk – in severely injured patients. The main mortality-predicting factors in trauma patients are those associated with basic human physiology and tissue perfusion status, coagulation adequacy, and resuscitation requirements. On the contrary, advanced age and the presence of comorbidities predispose patients to a poor outcome because of the loss of physiological reserves. Trauma resuscitation teams considering mortality prediction factors can not only guide resuscitation but also identify patients with high mortality risk who were previously considered less severely injured. |
format | Online Article Text |
id | pubmed-5994855 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-59948552018-06-22 Guiding Management in Severe Trauma: Reviewing Factors Predicting Outcome in Vastly Injured Patients Lilitsis, Emmanuel Xenaki, Sofia Athanasakis, Elias Papadakis, Eleftherios Syrogianni, Pavlina Chalkiadakis, George Chrysos, Emmanuel J Emerg Trauma Shock Review Article Trauma is one of the leading causes of death worldwide, with road traffic collisions, suicides, and homicides accounting for the majority of injury-related deaths. Since trauma mainly affects young age groups, it is recognized as a serious social and economic threat, as annually, almost 16,000 posttrauma individuals are expected to lose their lives and many more to end up disabled. The purpose of this research is to summarize current knowledge on factors predicting outcome – specifically mortality risk – in severely injured patients. Development of this review was mainly based on the systematic search of PubMed medical library, Cochrane database, and advanced trauma life support Guiding Manuals. The research was based on publications between 1994 and 2016. Although hypovolemic, obstructive, cardiogenic, and septic shock can all be seen in multi-trauma patients, hemorrhage-induced shock is by far the most common cause of shock. In this review, we summarize current knowledge on factors predicting outcome – more specifically mortality risk – in severely injured patients. The main mortality-predicting factors in trauma patients are those associated with basic human physiology and tissue perfusion status, coagulation adequacy, and resuscitation requirements. On the contrary, advanced age and the presence of comorbidities predispose patients to a poor outcome because of the loss of physiological reserves. Trauma resuscitation teams considering mortality prediction factors can not only guide resuscitation but also identify patients with high mortality risk who were previously considered less severely injured. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5994855/ /pubmed/29937635 http://dx.doi.org/10.4103/JETS.JETS_74_17 Text en Copyright: © 2018 Journal of Emergencies, Trauma, and Shock http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Review Article Lilitsis, Emmanuel Xenaki, Sofia Athanasakis, Elias Papadakis, Eleftherios Syrogianni, Pavlina Chalkiadakis, George Chrysos, Emmanuel Guiding Management in Severe Trauma: Reviewing Factors Predicting Outcome in Vastly Injured Patients |
title | Guiding Management in Severe Trauma: Reviewing Factors Predicting Outcome in Vastly Injured Patients |
title_full | Guiding Management in Severe Trauma: Reviewing Factors Predicting Outcome in Vastly Injured Patients |
title_fullStr | Guiding Management in Severe Trauma: Reviewing Factors Predicting Outcome in Vastly Injured Patients |
title_full_unstemmed | Guiding Management in Severe Trauma: Reviewing Factors Predicting Outcome in Vastly Injured Patients |
title_short | Guiding Management in Severe Trauma: Reviewing Factors Predicting Outcome in Vastly Injured Patients |
title_sort | guiding management in severe trauma: reviewing factors predicting outcome in vastly injured patients |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994855/ https://www.ncbi.nlm.nih.gov/pubmed/29937635 http://dx.doi.org/10.4103/JETS.JETS_74_17 |
work_keys_str_mv | AT lilitsisemmanuel guidingmanagementinseveretraumareviewingfactorspredictingoutcomeinvastlyinjuredpatients AT xenakisofia guidingmanagementinseveretraumareviewingfactorspredictingoutcomeinvastlyinjuredpatients AT athanasakiselias guidingmanagementinseveretraumareviewingfactorspredictingoutcomeinvastlyinjuredpatients AT papadakiseleftherios guidingmanagementinseveretraumareviewingfactorspredictingoutcomeinvastlyinjuredpatients AT syrogiannipavlina guidingmanagementinseveretraumareviewingfactorspredictingoutcomeinvastlyinjuredpatients AT chalkiadakisgeorge guidingmanagementinseveretraumareviewingfactorspredictingoutcomeinvastlyinjuredpatients AT chrysosemmanuel guidingmanagementinseveretraumareviewingfactorspredictingoutcomeinvastlyinjuredpatients |