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Deregulation of calcium homeostasis in Bcr-Abl-dependent chronic myeloid leukemia
BACKGROUND: Chronic myeloid leukemia (CML) results from hematopoietic stem cell transformation by the bcr-abl chimeric oncogene, encoding a 210 kDa protein with constitutive tyrosine kinase activity. In spite of the efficiency of tyrosine kinase inhibitors (TKI; Imatinib), other strategies are explo...
Autores principales: | Cabanas, Hélène, Harnois, Thomas, Magaud, Christophe, Cousin, Laëtitia, Constantin, Bruno, Bourmeyster, Nicolas, Déliot, Nadine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995172/ https://www.ncbi.nlm.nih.gov/pubmed/29899861 http://dx.doi.org/10.18632/oncotarget.25241 |
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