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A novel role of metal response element binding transcription factor 2 at the Hox gene cluster in the regulation of H3K27me3 by polycomb repressive complex 2

Polycomb repressive complex 2 (PRC2) is known to play an important role in the regulation of early embryonic development, differentiation, and cellular proliferation by introducing methyl groups onto lysine 27 of histone H3 (H3K27me3). PRC2 is tightly associated with silencing of Hox gene clusters a...

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Detalles Bibliográficos
Autores principales: Khan, Abdul Aziz, Ham, Seok-Jin, Yen, Le Ngoc, Lee, Haeng Lim, Huh, Jounghyun, Jeon, Hyeongrin, Kim, Myoung Hee, Roh, Tae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995182/
https://www.ncbi.nlm.nih.gov/pubmed/29899877
http://dx.doi.org/10.18632/oncotarget.25505