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Characterization and diagnostic application of genomic NPM-ALK fusion sequences in anaplastic large-cell lymphoma

Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) fusion genes resulting from the translocation t(2;5)(p23;q35) are present in almost 90% of childhood ALK-positive anaplastic large-cell lymphomas (ALCL). Detection and quantification of minimal disseminated disease (MDD) by measuring NPM-ALK fusion...

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Detalles Bibliográficos
Autores principales: Krumbholz, Manuela, Woessmann, Wilhelm, Zierk, Jakob, Seniuk, David, Ceppi, Paolo, Zimmermann, Martin, Singh, Vijay Kumar, Metzler, Markus, Damm-Welk, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995187/
https://www.ncbi.nlm.nih.gov/pubmed/29899875
http://dx.doi.org/10.18632/oncotarget.25489