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Characterization and diagnostic application of genomic NPM-ALK fusion sequences in anaplastic large-cell lymphoma
Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) fusion genes resulting from the translocation t(2;5)(p23;q35) are present in almost 90% of childhood ALK-positive anaplastic large-cell lymphomas (ALCL). Detection and quantification of minimal disseminated disease (MDD) by measuring NPM-ALK fusion...
Autores principales: | Krumbholz, Manuela, Woessmann, Wilhelm, Zierk, Jakob, Seniuk, David, Ceppi, Paolo, Zimmermann, Martin, Singh, Vijay Kumar, Metzler, Markus, Damm-Welk, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995187/ https://www.ncbi.nlm.nih.gov/pubmed/29899875 http://dx.doi.org/10.18632/oncotarget.25489 |
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