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Epigenetic dysregulation of TET2 in human glioblastoma

Ten-eleven translocation (TET) enzymes are frequently deregulated in cancer, but the underlying molecular mechanisms are still poorly understood. Here we report that TET2 shows frequent epigenetic alterations in human glioblastoma including DNA hypermethylation and hypo-hydroxymethylation, as well a...

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Detalles Bibliográficos
Autores principales:	García, María G., Carella, Antonella, Urdinguio, Rocío G., Bayón, Gustavo F., Lopez, Virginia, Tejedor, Juan Ramón, Sierra, Marta I., García-Toraño, Estela, Santamarina, Pablo, Perez, Raúl F., Mangas, Cristina, Astudillo, Aurora, Corte-Torres, M. Daniela, Sáenz-de-Santa-María, Inés, Chiara, María-Dolores, Fernández, Agustín F., Fraga, Mario F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995234/ https://www.ncbi.nlm.nih.gov/pubmed/29899831 http://dx.doi.org/10.18632/oncotarget.25406

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