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Concomitant driver mutations in advanced EGFR-mutated non-small-cell lung cancer and their impact on erlotinib treatment
BACKGROUND: Patients with EGFR-mutated non-small-cell lung cancer benefit from EGFR tyrosine kinase inhibitors (TKIs) like erlotinib. However, the efficacy may be impaired by driver mutations in other genes. METHODS: Five hundred and fourteen consecutive patients with NSCLC of all stages were tested...
Autores principales: | Jakobsen, Jan Nyrop, Santoni-Rugiu, Eric, Grauslund, Morten, Melchior, Linea, Sørensen, Jens Benn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995236/ https://www.ncbi.nlm.nih.gov/pubmed/29899852 http://dx.doi.org/10.18632/oncotarget.25490 |
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