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Efficient lysis of B-chronic lymphocytic leukemia cells by the plant-derived sesquiterpene alcohol α-bisabolol, a dual proapoptotic and antiautophagic agent
The sesquiterpene α-bisabolol (α-BSB) is a cytotoxic agent against acute leukemia and chronic myeloid leukemia cells. Here the profile of α-BSB citotoxicity was evaluated ex vivo in primary mononuclear blood cells isolated from 45 untreated B-chronic lymphocytic leukemia (B-CLL) patients. We studied...
Autores principales: | Rigo, Antonella, Ferrarini, Isacco, Bonalumi, Angela, Tecchio, Cristina, Montresor, Alessio, Laudanna, Carlo, Vinante, Fabrizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995246/ https://www.ncbi.nlm.nih.gov/pubmed/29899828 http://dx.doi.org/10.18632/oncotarget.25398 |
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