Cargando…

Contraceptive efficacy and safety of estradiol valerate/dienogest in a healthy female population: a multicenter, open-label, uncontrolled Phase III study

BACKGROUND: To investigate the efficacy and safety of a combined oral contraceptive containing estradiol valerate and dienogest (EV/DNG) in healthy Asian women. METHODS: In this multicenter Phase III study, women received oral EV/DNG in a 28-day regimen for 13 cycles. The primary efficacy endpoint w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Qi, Huang, Zirong, Ren, Mulan, Chang, Qing, Zhang, Zhongqi, Parke, Susanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995293/ https://www.ncbi.nlm.nih.gov/pubmed/29922096 http://dx.doi.org/10.2147/IJWH.S157056

Ejemplares similares

Endometrial safety of an oral contraceptive containing estradiol valerate and dienogest
por: Bitzer, Johannes, et al.
Publicado: (2011)

Contraception with estradiol valerate and dienogest: adherence to the method
por: Fruzzetti, Franca, et al.
Publicado: (2019)

Hemostatic Effects of a Novel Estradiol-Based Oral Contraceptive: An Open-Label, Randomized, Crossover Study of Estradiol Valerate/Dienogest versus Ethinylestradiol/Levonorgestrel
por: Klipping, Christine, et al.
Publicado: (2012)

Estradiol valerate and dienogest: a new approach to oral contraception
por: Kiley, Jessica W, et al.
Publicado: (2011)

Novel oral contraceptive for heavy menstrual bleeding: estradiol valerate and dienogest
por: Rafie, Sally, et al.
Publicado: (2013)

An overview of the development of combined oral contraceptives containing estradiol: focus on estradiol valerate/dienogest
por: Fruzzetti, Franca, et al.
Publicado: (2012)

Review of the safety, efficacy and patient acceptability of the combined dienogest/estradiol valerate contraceptive pill
por: Guida, Maurizio, et al.
Publicado: (2010)

Noncontraceptive benefits of the estradiol valerate/dienogest combined oral contraceptive: a review of the literature
por: Nappi, Rossella E, et al.
Publicado: (2014)

Continuation rates, bleeding profile acceptability, and satisfaction of women using an oral contraceptive pill containing estradiol valerate and dienogest versus a progestogen-only pill after switching from an ethinylestradiol-containing pill in a real-life setting: results of the CONTENT study
por: Briggs, Paula, et al.
Publicado: (2016)

Impact of estradiol-valerate/dienogest on work productivity and activities of daily living in European and Australian women with heavy menstrual bleeding
por: Wasiak, Radoslaw, et al.
Publicado: (2012)

Combined oral contraceptives containing estradiol valerate vs ethinylestradiol on coagulation: A randomized clinical trial
por: Haverinen, Annina H., et al.
Publicado: (2022)

Estradiol valerate and alcohol intake: dose-response assessments
por: Quirarte, Gina L, et al.
Publicado: (2007)

Estradiol Valerate Affects Hematological and Hemorheological Parameters in Rats
por: Barath, Barbara, et al.
Publicado: (2022)

Cycle scheduling for in vitro fertilization with oral contraceptive pills versus oral estradiol valerate: a randomized, controlled trial
por: Hauzman, Erik E, et al.
Publicado: (2013)

Stereological study of the effects of letrozole and estradiol valerate treatment on the ovary of rats
por: Noorafshan, Ali, et al.
Publicado: (2013)

Ethinylestradiol in combined hormonal contraceptive has a broader effect on serum proteome compared with estradiol valerate: a randomized controlled trial
por: Kangasniemi, M H, et al.
Publicado: (2022)

Effective treatment of heavy and/or prolonged menstrual bleeding without organic cause: pooled analysis of two multinational, randomised, double-blind, placebo-controlled trials of oestradiol valerate and dienogest
por: Fraser, Ian S, et al.
Publicado: (2011)

Changes of The Uterine Tissue in Rats with Polycystic Ovary Syndrome Induced by Estradiol Valerate
por: Mirabolghasemi, Ghadire, et al.
Publicado: (2017)

The Comparative Pharmaco- and Histokinetics of the Therapeutic Dose of Estradiol Valerate and Bromocriptine in Common Quails
por: Nadeem, Muhammad, et al.
Publicado: (2022)

Atherosclerosis-related biomarkers in women with endometriosis: The effects of dienogest and oral contraceptive therapy
por: Maeda, Eiko, et al.
Publicado: (2020)

The therapeutic effect of bromocriptine as mesylate and estradiol valerate on serum and blood biochemistry of common quails
por: ul- Abideen, Zain, et al.
Publicado: (2021)

Effect of exercise intensity on weight changes and sexual hormones (androstenedione and free testosterone) in female rats with estradiol valerate-induced PCOS
por: Miri, Maryamosadat, et al.
Publicado: (2014)

Pharmacological sympathetic denervation prevents the development of polycystic ovarian syndrome in rats injected with estradiol valerate
por: Espinoza, Julieta A., et al.
Publicado: (2018)

Effects of early estradiol valerate administration on bone turnover markers in surgically induced menopausal women
por: Vatrasresth, Jarika, et al.
Publicado: (2021)

Randomized study on the effectiveness of nomegestrol acetate plus 17β-estradiol oral contraceptive versus dienogest oral pill in women with suspected endometriosis‑associated chronic pelvic pain
por: Caruso, Salvatore, et al.
Publicado: (2022)

Dienogest and the Risk of Reoperation in Endometriosis
por: Seo, Yong-Soo, et al.
Publicado: (2021)

The Effect of Green Tea Extract on Reproductive Improvement in Estradiol Valerate-Induced Polycystic Ovarian Syndrome in Rat
por: Ghafurniyan, Habibeh, et al.
Publicado: (2015)

A Comparison of the Effects of Transdermal Estradiol and Estradiol Valerate on Endometrial Receptivity in Frozen-thawed Embryo Transfer Cycles: A Randomized Clinical Trial
por: Davar, Robab, et al.
Publicado: (2016)

Dienogest alone or dienogest combined with estrogens in the treatment of ovarian endometriomas, that is the question. A retrospective cohort study
por: Del Forno, Simona, et al.
Publicado: (2023)

Ultrasound-Assisted Esterification of Valeric Acid to Alkyl Valerates Promoted by Biosilicified Lipases
por: Cebrián-García, Soledad, et al.
Publicado: (2018)

In rats with estradiol valerate-induced polycystic ovary syndrome, the acute blockade of ovarian β-adrenoreceptors improve ovulation
por: Venegas, Berenice, et al.
Publicado: (2019)

A Clinical Study of the Effect of Estradiol Valerate on Sleep Disorders, Negative Emotions, and Quality of Life in Perimenopausal Women
por: Zhang, Jianfu, et al.
Publicado: (2021)

Therapeutic Effects of Eugenol in Polycystic Ovarian Rats Induced by Estradiol Valerate: A Histopathological and A Biochemical Study
por: Kokabiyan, Zahra, et al.
Publicado: (2022)

Dienogest in long-term treatment of endometriosis
por: Schindler, Adolf E
Publicado: (2011)

A phase 1, open‐label study to evaluate the drug interaction between islatravir (MK‐8591) and the oral contraceptive levonorgestrel/ethinyl estradiol in healthy adult females
por: Ankrom, Wendy, et al.
Publicado: (2021)

Effect of 150 kHz electromagnetic radiation on the development of polycystic ovaries induced by estradiol Valerate in Sprague Dawley rats
por: Mohammed, Stephanie, et al.
Publicado: (2021)

Brovalol, a New Valeric
Publicado: (1909)

Efficacy and Tolerability of Generic Mirtazapine (Mirtax) for Major Depressive Disorder: Multicenter, Open-label, Uncontrolled, Prospective Study
por: Song, Hoo Rim, et al.
Publicado: (2015)

Infliximab for pediatric patients with Crohn’s disease: A Phase 3, open-label, uncontrolled, multicenter trial in Japan
por: Tajiri, Hitoshi, et al.
Publicado: (2018)

Subcutaneous tocilizumab in adults with severe and critical COVID-19: A prospective open-label uncontrolled multicenter trial
por: Malekzadeh, Reza, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_h2hadjs44sagm2fr51nlg4acjf