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Deletion of endothelial arginase 1 does not improve vasomotor function in diabetic mice
Endothelial arginase 1 was ablated to assess whether this prevents hyperglycemia‐induced endothelial dysfunction by improving arginine availability for nitric oxide production. Endothelial Arg1‐deficient mice (Arg1‐KO(T) (ie2)) were generated by crossing Arg1 (fl/fl) (controls) with Tie2Cre (tg/−) m...
Autores principales: | Chennupati, Ramesh, Meens, Merlijn J., Janssen, Ben J., van Dijk, Paul, Hakvoort, Theodorus B. M., Lamers, Wouter H., De Mey, Jo G. R., Koehler, S. Eleonore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995309/ https://www.ncbi.nlm.nih.gov/pubmed/29890043 http://dx.doi.org/10.14814/phy2.13717 |
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