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The POU/Oct Transcription Factor Nubbin Controls the Balance of Intestinal Stem Cell Maintenance and Differentiation by Isoform-Specific Regulation

Drosophila POU/Oct transcription factors are required for many developmental processes, but their putative regulation of adult stem cell activity has not been investigated. Here, we show that Nubbin (Nub)/Pdm1, homologous to mammalian OCT1/POU2F1 and related to OCT4/POU5F1, is expressed in gut epith...

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Detalles Bibliográficos
Autores principales:	Tang, Xiongzhuo, Zhao, Yunpo, Buchon, Nicolas, Engström, Ylva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995344/ https://www.ncbi.nlm.nih.gov/pubmed/29681543 http://dx.doi.org/10.1016/j.stemcr.2018.03.014

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