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Humoral and cellular immune responses to Yersinia pestis Pla antigen in humans immunized with live plague vaccine

BACKGROUND: To establish correlates of human immunity to the live plague vaccine (LPV), we analyzed parameters of cellular and antibody response to the plasminogen activator Pla of Y. pestis. This outer membrane protease is an essential virulence factor that is steadily expressed by Y. pestis. METHO...

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Detalles Bibliográficos
Autores principales: Feodorova, Valentina A., Lyapina, Anna M., Khizhnyakova, Maria A., Zaitsev, Sergey S., Sayapina, Lidiya V., Arseneva, Tatiana E., Trukhachev, Alexey L., Lebedeva, Svetlana A., Telepnev, Maxim V., Ulianova, Onega V., Lyapina, Elena P., Ulyanov, Sergey S., Motin, Vladimir L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995359/
https://www.ncbi.nlm.nih.gov/pubmed/29889829
http://dx.doi.org/10.1371/journal.pntd.0006511

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