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Pharmaceutical iron formulations do not cross a model of the human blood-brain barrier
Whether iron formulations used therapeutically for a variety of conditions involving iron deficiency can deliver iron to the brain is a significant clinical question given the impact that iron loading has on the brain in neurodegenerative diseases. In this study, we examine the ability of 5 pharmace...
Autores principales: | Chiou, Brian, Neal, Emma H., Bowman, Aaron B., Lippmann, Ethan S., Simpson, Ian A., Connor, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995392/ https://www.ncbi.nlm.nih.gov/pubmed/29889872 http://dx.doi.org/10.1371/journal.pone.0198775 |
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