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p73 Alternative Splicing: Exploring a Biological Role for the C-Terminal Isoforms
p73 (encoded by TP73 gene) is a p53 related protein that functions as a transcriptional factor. Similarly to p53, following DNA damage, p73 is stabilized and activated and controls expression of target genes that are involved in the regulation of cycle arrest and apoptosis. However, great complexity...
Autores principales: | Vikhreva, Polina, Melino, Gerry, Amelio, Ivano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995411/ https://www.ncbi.nlm.nih.gov/pubmed/29733853 http://dx.doi.org/10.1016/j.jmb.2018.04.034 |
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