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D-cis-Diltiazem Can Produce Oxidative Stress in Healthy Depolarized Rods In Vivo

PURPOSE: New perspectives are needed to understand decades of contradictory reports on the neuroprotective effects of the Cav1.2 L-type calcium channel blocker d-cis-diltiazem in retinitis pigmentosa (RP) models. Here, we address, in vivo, the following two knowledge gaps regarding d-cis-diltiazem&#...

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Detalles Bibliográficos
Autores principales: Berkowitz, Bruce A., Podolsky, Robert H., Farrell, Benjamin, Lee, Hojun, Trepanier, Christopher, Berri, Ali M., Dernay, Kristin, Graffice, Emma, Shafie-Khorassani, Fatema, Kern, Timothy S., Roberts, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995482/
https://www.ncbi.nlm.nih.gov/pubmed/30025125
http://dx.doi.org/10.1167/iovs.18-23829