Integrated Stress Response and Decreased ECM in Cultured Stromal Cells From Keratoconus Corneas

PURPOSE: Keratoconus (KC) is a multifactorial disease where progressive thinning and weakening of the cornea leads to loss of visual acuity. Although the underlying etiology is poorly understood, a major endpoint is a dysfunctional stromal connective tissue matrix. Using multiple individual KC corne...

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Detalles Bibliográficos
Autores principales: Foster, James W., Shinde, Vishal, Soiberman, Uri S., Sathe, Gajanan, Liu, Sheng, Wan, Julius, Qian, Jiang, Dauoud, Yassine, Pandey, Akhilesh, Jun, Albert S., Chakravarti, Shukti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995483/
https://www.ncbi.nlm.nih.gov/pubmed/30029277
http://dx.doi.org/10.1167/iovs.18-24367

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