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Dynamics of ribosomes and release factors during translation termination in E. coli

Release factors RF1 and RF2 promote hydrolysis of peptidyl-tRNA during translation termination. The GTPase RF3 promotes recycling of RF1 and RF2. Using single molecule FRET and biochemical assays, we show that ribosome termination complexes that carry two factors, RF1–RF3 or RF2–RF3, are dynamic and...

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Detalles Bibliográficos
Autores principales:	Adio, Sarah, Sharma, Heena, Senyushkina, Tamara, Karki, Prajwal, Maracci, Cristina, Wohlgemuth, Ingo, Holtkamp, Wolf, Peske, Frank, Rodnina, Marina V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995542/ https://www.ncbi.nlm.nih.gov/pubmed/29889659 http://dx.doi.org/10.7554/eLife.34252

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