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Simplifying [(18)F]GE-179 PET: are both arterial blood sampling and 90-min acquisitions essential?

INTRODUCTION: The NMDA receptor radiotracer [(18)F]GE-179 has been used with 90-min scans and arterial plasma input functions. We explored whether (1) arterial blood sampling is avoidable and (2) shorter scans are feasible. METHODS: For 20 existing [(18)F]GE-179 datasets, we generated (1) standardis...

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Detalles Bibliográficos
Autores principales: McGinnity, Colm J., Riaño Barros, Daniela A., Trigg, William, Brooks, David J., Hinz, Rainer, Duncan, John S., Koepp, Matthias J., Hammers, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995767/
https://www.ncbi.nlm.nih.gov/pubmed/29892810
http://dx.doi.org/10.1186/s13550-018-0396-2

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