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(−)-Gochnatiolide B, synthesized from dehydrocostuslactone, exhibits potent anti-bladder cancer activity in vitro and in vivo

With limited success achieved in bladder cancer patient management, novel agents are in urgent need for the purpose of therapy and prevention. As a sesquiterpenoid dimmer isolated from Gochnatia pomculat, (−)-gochnatiolide B has been bio-mimetically synthesized in multiple steps with a poor yield, w...

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Detalles Bibliográficos
Autores principales:	Chen, Yuwen, Li, Wenhua, Zeng, Zhongqiu, Tang, Yaxiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995859/ https://www.ncbi.nlm.nih.gov/pubmed/29891980 http://dx.doi.org/10.1038/s41598-018-27036-6

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