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Docetaxel Treatment in PTEN- and ERG-aberrant Metastatic Prostate Cancers
BACKGROUND: Loss of PTEN is a common genomic aberration in castration-resistant prostate cancer (CRPC) and is frequently concurrent with ERG rearrangements, causing resistance to next-generation hormonal treatment (NGHT) including abiraterone. The relationship between PTEN loss and docetaxel sensiti...
Autores principales: | Rescigno, Pasquale, Lorente, David, Dolling, David, Ferraldeschi, Roberta, Rodrigues, Daniel Nava, Riisnaes, Ruth, Miranda, Susana, Bianchini, Diletta, Zafeiriou, Zafeiris, Sideris, Spyridon, Ferreira, Ana, Figueiredo, Ines, Sumanasuriya, Semini, Mateo, Joaquin, Perez-Lopez, Raquel, Sharp, Adam, Tunariu, Nina, de Bono, Johann S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995869/ https://www.ncbi.nlm.nih.gov/pubmed/29911685 http://dx.doi.org/10.1016/j.euo.2018.02.006 |
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