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Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice

Severe acute pancreatitis is a lethal inflammatory disease frequently accompanied by pancreatic necrosis. We aimed to identify a key regulator in the development of pancreatic necrosis. A cytokine/chemokine array using sera from patients with acute pancreatitis (AP) revealed that serum CXCL16 levels...

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Detalles Bibliográficos
Autores principales: Sakuma, Yojiro, Kodama, Yuzo, Eguchi, Takaaki, Uza, Norimitsu, Tsuji, Yoshihisa, Shiokawa, Masahiro, Maruno, Takahisa, Kuriyama, Katsutoshi, Nishikawa, Yoshihiro, Yamauchi, Yuki, Tsuda, Motoyuki, Ueda, Tatsuki, Matsumori, Tomoaki, Morita, Toshihiro, Tomono, Teruko, Kakiuchi, Nobuyuki, Mima, Atsushi, Sogabe, Yuko, Marui, Saiko, Kuwada, Takeshi, Okada, Akihiko, Watanabe, Tomohiro, Nakase, Hiroshi, Chiba, Tsutomu, Seno, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995899/
https://www.ncbi.nlm.nih.gov/pubmed/29891873
http://dx.doi.org/10.1038/s41598-018-27200-y