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Association of Inflammatory Responses and ECM Disorganization with HMGB1 Upregulation and NLRP3 Inflammasome Activation in the Injured Rotator Cuff Tendon
Inflammation and extracellular matrix (ECM) disorganization following the rotator cuff tendon injuries (RCTI) delay the repair and healing process and the molecular mechanisms underlying RCTI pathology are largely unknown. Here, we examined the role of HMGB1 and NLRP3 inflammasome pathway in the inf...
Autores principales: | Thankam, Finosh G., Roesch, Zachary K., Dilisio, Matthew F., Radwan, Mohamed M., Kovilam, Anuradha, Gross, R. Michael, Agrawal, Devendra K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995925/ https://www.ncbi.nlm.nih.gov/pubmed/29891998 http://dx.doi.org/10.1038/s41598-018-27250-2 |
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