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β-apo-10′-carotenoids support normal embryonic development during vitamin A deficiency
Vitamin A deficiency is still a public health concern affecting millions of pregnant women and children. Retinoic acid, the active form of vitamin A, is critical for proper mammalian embryonic development. Embryos can generate retinoic acid from maternal circulating β-carotene upon oxidation of reti...
Autores principales: | Spiegler, Elizabeth, Kim, Youn-Kyung, Hoyos, Beatrice, Narayanasamy, Sureshbabu, Jiang, Hongfeng, Savio, Nicole, Curley, Robert W., Harrison, Earl H., Hammerling, Ulrich, Quadro, Loredana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995931/ https://www.ncbi.nlm.nih.gov/pubmed/29892071 http://dx.doi.org/10.1038/s41598-018-27071-3 |
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