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SIRT1 promotes formation of breast cancer through modulating Akt activity
The silent information regulation factor 1 (sirtuin Type 1, SIRT1), as a kind of NAD(+) dependent class III histone deacetylation enzyme, has been found to be involved in tumor proliferation, invasion, and metastasis. The roles of SIRTl in breast cancer is multifaceted depending on its substrate fro...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995935/ https://www.ncbi.nlm.nih.gov/pubmed/29896286 http://dx.doi.org/10.7150/jca.24275 |