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SIRT1 promotes formation of breast cancer through modulating Akt activity

The silent information regulation factor 1 (sirtuin Type 1, SIRT1), as a kind of NAD(+) dependent class III histone deacetylation enzyme, has been found to be involved in tumor proliferation, invasion, and metastasis. The roles of SIRTl in breast cancer is multifaceted depending on its substrate fro...

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Detalles Bibliográficos
Autores principales: Jin, Xiaoxia, Wei, Yingze, Xu, Feng, Zhao, Min, Dai, Kui, Shen, Rong, Yang, Shuyun, Zhang, Nong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995935/
https://www.ncbi.nlm.nih.gov/pubmed/29896286
http://dx.doi.org/10.7150/jca.24275

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