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Microsomal Prostaglandin E Synthase-1 Plays a Critical Role in Long-term Motility Dysfunction after Bowel Obstruction

Motility dysfunction is present not only during bowel obstruction (BO), but after obstruction is resolved. Previous studies found that lumen distension associated mechano-transcription of COX-2 and production of PGE(2) in gut smooth muscle cells (SMC) account for motility dysfunction during obstruct...

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Detalles Bibliográficos
Autores principales:	Lin, You-Min, Fu, Yu, Hegde, Shrilakshmi, Tang, Yanbo, Radhakrishnan, Ravi, Shi, Xuan-Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995953/ https://www.ncbi.nlm.nih.gov/pubmed/29891860 http://dx.doi.org/10.1038/s41598-018-27230-6

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