Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During β-Adrenergic and Muscarinic Receptor Activation

Sympathetic and vagal activation is linked to atrial arrhythmogenesis. Here we investigated the small conductance Ca(2+)-activated K(+) (SK)-channel pore-blocker N-(pyridin-2-yl)-4-(pyridine-2-yl)thiazol-2-amine (ICA) on action potential (AP) and atrial fibrillation (AF) parameters in isolated rat a...

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Detalles Bibliográficos
Autores principales: Skibsbye, Lasse, Bengaard, Anne K., Uldum-Nielsen, A. M., Boddum, Kim, Christ, Torsten, Jespersen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996028/
https://www.ncbi.nlm.nih.gov/pubmed/29922167
http://dx.doi.org/10.3389/fphys.2018.00510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996028/
https://www.ncbi.nlm.nih.gov/pubmed/29922167
http://dx.doi.org/10.3389/fphys.2018.00510

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