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High Mobility Group Box 1 Promotes Aortic Calcification in Chronic Kidney Disease via the Wnt/β-Catenin Pathway
Vascular calcification (VC) is common in chronic kidney disease (CKD), where cardiovascular mortality remains the leading cause of death. Here, we examined the role of high-mobility group box1 (HMGB1), a nuclear DNA-binding protein involved in inflammation, in aortic calcification and renal dysfunct...
Autores principales: | Jin, Xiucai, Rong, Shu, Yuan, Weijie, Gu, Lijie, Jia, Jieshuang, Wang, Ling, Yu, Honglei, Zhuge, Yifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996195/ https://www.ncbi.nlm.nih.gov/pubmed/29922171 http://dx.doi.org/10.3389/fphys.2018.00665 |
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