Dataset of cathepsin L-like CP inhibition of Naegleria fowleri and Acanthamoeba castellanii by ppTvCP4r from Trichomonas vaginalis

The recombinant TvCP4 prepro region (ppTvCP4r) acts as an exogenous inhibitor of cathepsin L-like CPs from Trichomonas vaginalis (Cárdenas-Guerra et al., 2015 [1]). Here, we present the dataset of the trichomonad ppTvCP4r inhibitory effect against the CP proteolytic activities from other microorgani...

Descripción completa

Detalles Bibliográficos
Autores principales: Cárdenas-Guerra, Rosa E., Martínez-Castillo, Moisés, Ortega-López, Jaime, Shibayama, Mineko, Arroyo, Rossana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Cell biology   
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996237/
https://www.ncbi.nlm.nih.gov/pubmed/29896525
http://dx.doi.org/10.1016/j.dib.2018.03.029
_version_ 1783330803322716160
author Cárdenas-Guerra, Rosa E.
Martínez-Castillo, Moisés
Ortega-López, Jaime
Shibayama, Mineko
Arroyo, Rossana
author_facet Cárdenas-Guerra, Rosa E.
Martínez-Castillo, Moisés
Ortega-López, Jaime
Shibayama, Mineko
Arroyo, Rossana
author_sort Cárdenas-Guerra, Rosa E.
collection PubMed
description The recombinant TvCP4 prepro region (ppTvCP4r) acts as an exogenous inhibitor of cathepsin L-like CPs from Trichomonas vaginalis (Cárdenas-Guerra et al., 2015 [1]). Here, we present the dataset of the trichomonad ppTvCP4r inhibitory effect against the CP proteolytic activities from other microorganisms, such as Naegleria fowleri and Acanthamoeba castellanii free-living amoeba. The proteolytic activity inhibition of total crude extracts (TCEs) of N. fowleri and A. castellanii was determined and recorded using a fluorogenic substrate specific for cathepsin L CPs without or with a ppTvCP4r treatment at different concentrations and pH.
format Online
Article
Text
id pubmed-5996237
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-59962372018-06-12 Dataset of cathepsin L-like CP inhibition of Naegleria fowleri and Acanthamoeba castellanii by ppTvCP4r from Trichomonas vaginalis Cárdenas-Guerra, Rosa E. Martínez-Castillo, Moisés Ortega-López, Jaime Shibayama, Mineko Arroyo, Rossana Data Brief Cell biology    The recombinant TvCP4 prepro region (ppTvCP4r) acts as an exogenous inhibitor of cathepsin L-like CPs from Trichomonas vaginalis (Cárdenas-Guerra et al., 2015 [1]). Here, we present the dataset of the trichomonad ppTvCP4r inhibitory effect against the CP proteolytic activities from other microorganisms, such as Naegleria fowleri and Acanthamoeba castellanii free-living amoeba. The proteolytic activity inhibition of total crude extracts (TCEs) of N. fowleri and A. castellanii was determined and recorded using a fluorogenic substrate specific for cathepsin L CPs without or with a ppTvCP4r treatment at different concentrations and pH. Elsevier 2018-03-13 /pmc/articles/PMC5996237/ /pubmed/29896525 http://dx.doi.org/10.1016/j.dib.2018.03.029 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Cell biology   
Cárdenas-Guerra, Rosa E.
Martínez-Castillo, Moisés
Ortega-López, Jaime
Shibayama, Mineko
Arroyo, Rossana
Dataset of cathepsin L-like CP inhibition of Naegleria fowleri and Acanthamoeba castellanii by ppTvCP4r from Trichomonas vaginalis
title Dataset of cathepsin L-like CP inhibition of Naegleria fowleri and Acanthamoeba castellanii by ppTvCP4r from Trichomonas vaginalis
title_full Dataset of cathepsin L-like CP inhibition of Naegleria fowleri and Acanthamoeba castellanii by ppTvCP4r from Trichomonas vaginalis
title_fullStr Dataset of cathepsin L-like CP inhibition of Naegleria fowleri and Acanthamoeba castellanii by ppTvCP4r from Trichomonas vaginalis
title_full_unstemmed Dataset of cathepsin L-like CP inhibition of Naegleria fowleri and Acanthamoeba castellanii by ppTvCP4r from Trichomonas vaginalis
title_short Dataset of cathepsin L-like CP inhibition of Naegleria fowleri and Acanthamoeba castellanii by ppTvCP4r from Trichomonas vaginalis
title_sort dataset of cathepsin l-like cp inhibition of naegleria fowleri and acanthamoeba castellanii by pptvcp4r from trichomonas vaginalis
topic Cell biology   
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996237/
https://www.ncbi.nlm.nih.gov/pubmed/29896525
http://dx.doi.org/10.1016/j.dib.2018.03.029
work_keys_str_mv AT cardenasguerrarosae datasetofcathepsinllikecpinhibitionofnaegleriafowleriandacanthamoebacastellaniibypptvcp4rfromtrichomonasvaginalis
AT martinezcastillomoises datasetofcathepsinllikecpinhibitionofnaegleriafowleriandacanthamoebacastellaniibypptvcp4rfromtrichomonasvaginalis
AT ortegalopezjaime datasetofcathepsinllikecpinhibitionofnaegleriafowleriandacanthamoebacastellaniibypptvcp4rfromtrichomonasvaginalis
AT shibayamamineko datasetofcathepsinllikecpinhibitionofnaegleriafowleriandacanthamoebacastellaniibypptvcp4rfromtrichomonasvaginalis
AT arroyorossana datasetofcathepsinllikecpinhibitionofnaegleriafowleriandacanthamoebacastellaniibypptvcp4rfromtrichomonasvaginalis

Ejemplares similares