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Low GRK2 Underlies Hyperalgesic Priming by Glial Cell-Derived Neurotrophic Factor
Background: We recently identified the balance between the level of G protein coupled receptor kinase 2 (GRK2) and Epac1 in nociceptors as a key factor in the transition from acute to chronic pain that occurs in mice ‘primed’ by an inflammatory stimulus. Here, we examined the contribution of GRK2 an...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996251/ https://www.ncbi.nlm.nih.gov/pubmed/29922165 http://dx.doi.org/10.3389/fphar.2018.00592 |