Data from a targeted proteomics approach to discover biomarkers in saliva for the clinical diagnosis of periodontitis

This study focused on the search for new biomarkers based on liquid chromatography-multiple reaction monitoring (LC-MRM) proteomics profiling of whole saliva from patients with periodontitis compared to healthy subjects. The LC-MRM profiling approach is a new and innovative method that has already b...

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Detalles Bibliográficos
Autores principales: Orti, V., Mertens, B., Vialaret, J., Gibert, P., Relaño-Ginés, A., Lehmann, S., Deville de Périère, D., Hirtz, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Proteomics and Biochemistry   
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996262/
https://www.ncbi.nlm.nih.gov/pubmed/29900194
http://dx.doi.org/10.1016/j.dib.2018.03.036
Descripción
Sumario:This study focused on the search for new biomarkers based on liquid chromatography-multiple reaction monitoring (LC-MRM) proteomics profiling of whole saliva from patients with periodontitis compared to healthy subjects. The LC-MRM profiling approach is a new and innovative method that has already been validated for the absolute and multiplexed quantification of biomarkers in several diseases. The dataset for this study was produced using LC-MRM to monitor protein levels in a multiplex assay, it provides clinical information on salivary biomarkers of periodontitis. The data presented here is an extension of our recently published research article (Mertens et al., 2017) [1].

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