Cargando…
Data on the expression of CXCR3 ligands and pro-inflammatory cytokines in macrophages and CD4(+) T cells after stimuli of CXCR3 ligands
C-X-C motif chemokine receptor 3 (CXCR3) is a G protein-coupled receptor for three ligands which are C-X-C motif chemokine 9 (CXCL9), CXCL10, and CXCL11 [1]. Previously we have reported that CXCL10 promotes pro-inflammatory cytokine expression, and forms positive feedback loop [2], [3]. In the prese...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996269/ https://www.ncbi.nlm.nih.gov/pubmed/29900211 http://dx.doi.org/10.1016/j.dib.2018.03.042 |
_version_ | 1783330812462104576 |
---|---|
author | Kim, Bongjun Lee, Jong-Ho Jin, Won Jong Kim, Hong-Hee Ha, Hyunil Lee, Zang Hee |
author_facet | Kim, Bongjun Lee, Jong-Ho Jin, Won Jong Kim, Hong-Hee Ha, Hyunil Lee, Zang Hee |
author_sort | Kim, Bongjun |
collection | PubMed |
description | C-X-C motif chemokine receptor 3 (CXCR3) is a G protein-coupled receptor for three ligands which are C-X-C motif chemokine 9 (CXCL9), CXCL10, and CXCL11 [1]. Previously we have reported that CXCL10 promotes pro-inflammatory cytokine expression, and forms positive feedback loop [2], [3]. In the present study, we described mRNA expression of CXCL9 and CXCL11 under CXCL10 stimuli in the presence or absence of CXCR3 antagonist, JN-2 in bone marrow-derived macrophages (BMMs) and CD4(+) T cells. In addition, we examined pro-inflammatory cytokine expression under CXCL9 or CXCL11 stimuli in BMMs and CD4(+) T cells. |
format | Online Article Text |
id | pubmed-5996269 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-59962692018-06-13 Data on the expression of CXCR3 ligands and pro-inflammatory cytokines in macrophages and CD4(+) T cells after stimuli of CXCR3 ligands Kim, Bongjun Lee, Jong-Ho Jin, Won Jong Kim, Hong-Hee Ha, Hyunil Lee, Zang Hee Data Brief Cell biology C-X-C motif chemokine receptor 3 (CXCR3) is a G protein-coupled receptor for three ligands which are C-X-C motif chemokine 9 (CXCL9), CXCL10, and CXCL11 [1]. Previously we have reported that CXCL10 promotes pro-inflammatory cytokine expression, and forms positive feedback loop [2], [3]. In the present study, we described mRNA expression of CXCL9 and CXCL11 under CXCL10 stimuli in the presence or absence of CXCR3 antagonist, JN-2 in bone marrow-derived macrophages (BMMs) and CD4(+) T cells. In addition, we examined pro-inflammatory cytokine expression under CXCL9 or CXCL11 stimuli in BMMs and CD4(+) T cells. Elsevier 2018-03-15 /pmc/articles/PMC5996269/ /pubmed/29900211 http://dx.doi.org/10.1016/j.dib.2018.03.042 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Cell biology Kim, Bongjun Lee, Jong-Ho Jin, Won Jong Kim, Hong-Hee Ha, Hyunil Lee, Zang Hee Data on the expression of CXCR3 ligands and pro-inflammatory cytokines in macrophages and CD4(+) T cells after stimuli of CXCR3 ligands |
title | Data on the expression of CXCR3 ligands and pro-inflammatory cytokines in macrophages and CD4(+) T cells after stimuli of CXCR3 ligands |
title_full | Data on the expression of CXCR3 ligands and pro-inflammatory cytokines in macrophages and CD4(+) T cells after stimuli of CXCR3 ligands |
title_fullStr | Data on the expression of CXCR3 ligands and pro-inflammatory cytokines in macrophages and CD4(+) T cells after stimuli of CXCR3 ligands |
title_full_unstemmed | Data on the expression of CXCR3 ligands and pro-inflammatory cytokines in macrophages and CD4(+) T cells after stimuli of CXCR3 ligands |
title_short | Data on the expression of CXCR3 ligands and pro-inflammatory cytokines in macrophages and CD4(+) T cells after stimuli of CXCR3 ligands |
title_sort | data on the expression of cxcr3 ligands and pro-inflammatory cytokines in macrophages and cd4(+) t cells after stimuli of cxcr3 ligands |
topic | Cell biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996269/ https://www.ncbi.nlm.nih.gov/pubmed/29900211 http://dx.doi.org/10.1016/j.dib.2018.03.042 |
work_keys_str_mv | AT kimbongjun dataontheexpressionofcxcr3ligandsandproinflammatorycytokinesinmacrophagesandcd4tcellsafterstimuliofcxcr3ligands AT leejongho dataontheexpressionofcxcr3ligandsandproinflammatorycytokinesinmacrophagesandcd4tcellsafterstimuliofcxcr3ligands AT jinwonjong dataontheexpressionofcxcr3ligandsandproinflammatorycytokinesinmacrophagesandcd4tcellsafterstimuliofcxcr3ligands AT kimhonghee dataontheexpressionofcxcr3ligandsandproinflammatorycytokinesinmacrophagesandcd4tcellsafterstimuliofcxcr3ligands AT hahyunil dataontheexpressionofcxcr3ligandsandproinflammatorycytokinesinmacrophagesandcd4tcellsafterstimuliofcxcr3ligands AT leezanghee dataontheexpressionofcxcr3ligandsandproinflammatorycytokinesinmacrophagesandcd4tcellsafterstimuliofcxcr3ligands |