Cargando…

The Role of the Insulin-Like Growth Factor 1 Pathway in Immune Tumor Microenvironment and Its Clinical Ramifications in Gynecologic Malignancies

Treatment of patients with gynecologic malignancies diagnosed at advanced stages remains a therapeutic challenge. Survival rates of these patients remain significantly low, despite surgery and chemotherapy. Advances in understanding the role of the immune system in the pathogenesis of cancer have le...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yahya, Muna Alemi, Sharon, Shilhav Meisel, Hantisteanu, Shay, Hallak, Mordechai, Bruchim, Ilan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996273/ https://www.ncbi.nlm.nih.gov/pubmed/29922232 http://dx.doi.org/10.3389/fendo.2018.00297

Ejemplares similares

IGF1R Axis Inhibition Restores Dendritic Cell Antitumor Response in Ovarian Cancer
por: Somri-Gannam, Lina, et al.
Publicado: (2020)

Oncogenic fusion proteins adopt the insulin-like growth factor signaling pathway
por: Werner, Haim, et al.
Publicado: (2018)

ZYG11A Is Expressed in Epithelial Ovarian Cancer and Correlates With Low Grade Disease
por: Achlaug, Laris, et al.
Publicado: (2021)

Lipid droplets in granulosa cells are correlated with reduced pregnancy rates
por: Raviv, Shira, et al.
Publicado: (2020)

Genome-Wide Analyses Identify Filamin-A As a Novel Downstream Target for Insulin and IGF1 Action
por: Aizen, Daniel, et al.
Publicado: (2018)

The Impact of Lifestyle on Sperm Function, Telomere Length, and IVF Outcomes
por: Sharqawi, Moamina, et al.
Publicado: (2022)

The IGF Hormonal Network in Endometrial Cancer: Functions, Regulation, and Targeting Approaches
por: Bruchim, Ilan, et al.
Publicado: (2014)

TMPRSS2-ERG fusion protein regulates insulin-like growth factor-1 receptor (IGF1R) gene expression in prostate cancer: involvement of transcription factor Sp1
por: Sharon, Shilhav Meisel, et al.
Publicado: (2016)

The Mechanism of Action of the Histone Deacetylase Inhibitor Vorinostat Involves Interaction with the Insulin-Like Growth Factor Signaling Pathway
por: Sarfstein, Rive, et al.
Publicado: (2011)

Insulin-like Growth Factor 1 Signaling Axis Meets p53 Genome Protection Pathways
por: Werner, Haim, et al.
Publicado: (2016)

Insulin-like growth factor-1 signaling in the tumor microenvironment: Carcinogenesis, cancer drug resistance, and therapeutic potential
por: Nwabo Kamdje, Armel H., et al.
Publicado: (2022)

Human NK Cell Diversity in Viral Infection: Ramifications of Ramification
por: Strauss-Albee, Dara M., et al.
Publicado: (2016)

Ramification of indexing of medical journals
por: Chakravarthy, M, et al.
Publicado: (2013)

Insulin-Like Growth Factor Pathway and the Thyroid
por: Smith, Terry J.
Publicado: (2021)

The Emerging Role of Insulin and Insulin-Like Growth Factor Signaling in Cancer Stem Cells
por: Malaguarnera, Roberta, et al.
Publicado: (2014)

The Structural Determinants of Insulin-Like Peptide 3 Activity
por: Bathgate, Ross A. D., et al.
Publicado: (2012)

Insulin-Like Factor 3 and the HPG Axis in the Male
por: Ivell, Richard, et al.
Publicado: (2014)

Synthetic biology: ethical ramifications 2009
por: Rabinow, Paul, et al.
Publicado: (2009)

Microbiome and Health: Ramifications of Intelligent Deception
por: Stefano, George B., et al.
Publicado: (2018)

Global Ramifications of Dust and Sandstorm Microbiota
por: Behzad, Hayedeh, et al.
Publicado: (2018)

Premenstrual syndrome and its psychiatric ramifications
por: Qureshi, Naseem A.
Publicado: (2004)

Healthcare Teams: Terminology, Confusion, and Ramifications
por: Martin, Aleysha K, et al.
Publicado: (2022)

Insulin-Like Growth Factor Binding Proteins in Autoimmune Diseases
por: Ding, Huihua, et al.
Publicado: (2018)

Insulin-Like Growth Factor-Binding Proteins of Teleost Fishes
por: Garcia de la Serrana, Daniel, et al.
Publicado: (2018)

Differential Effects of Camel Milk on Insulin Receptor Signaling – Toward Understanding the Insulin-Like Properties of Camel Milk
por: Abdulrahman, Abdulrasheed O., et al.
Publicado: (2016)

All-Atom Structural Models of the Transmembrane Domains of Insulin and Type 1 Insulin-Like Growth Factor Receptors
por: Mohammadiarani, Hossein, et al.
Publicado: (2016)

Aldosterone in Gynecology and Its Involvement on the Risk of Hypertension in Pregnancy
por: Sabbadin, Chiara, et al.
Publicado: (2019)

The Relevant Participation of Prolactin in the Genesis and Progression of Gynecological Cancers
por: Ramírez-de-Arellano, Adrián, et al.
Publicado: (2021)

Sarcoid-Like Mediastinal Lymphadenopathy in Gynecologic Malignancy
por: Lashari, Bilal H., et al.
Publicado: (2018)

Ligand-Mediated Endocytosis and Trafficking of the Insulin-Like Growth Factor Receptor I and Insulin Receptor Modulate Receptor Function
por: Morcavallo, Alaide, et al.
Publicado: (2014)

Insulin-Like Growth Factor Binding Proteins: A Structural Perspective
por: Forbes, Briony E., et al.
Publicado: (2012)

Insulin-like growth factor-II: new roles for an old actor
por: Cianfarani, Stefano
Publicado: (2012)

Insulin-Like Peptide Signaling in Mosquitoes: The Road Behind and the Road Ahead
por: Sharma, Arvind, et al.
Publicado: (2019)

Insulin-Like Growth Factor Binding Protein-5 in Physiology and Disease
por: Duan, Cunming, et al.
Publicado: (2020)

Growth Hormone and Insulin-Like Growth Factor Action in Reproductive Tissues
por: Ipsa, Emina, et al.
Publicado: (2019)

Insulin-like growth factors and aging: lessons from Laron syndrome
por: Werner, Haim, et al.
Publicado: (2023)

Effects of Transport Duration and Environmental Conditions in Winter or Summer on the Concentrations of Insulin-Like Growth Factors and Insulin-Like Growth Factor-Binding Proteins in the Plasma of Market-Weight Pigs
por: Wirthgen, Elisa, et al.
Publicado: (2018)

Molecular Characterization of the Insulin-Like Androgenic Gland Hormone in the Swimming Crab, Portunus trituberculatus, and Its Involvement in the Insulin Signaling System
por: Jiang, Qinghua, et al.
Publicado: (2020)

Corrigendum: Insulin-Like Growth Factor Binding Protein-5 in Physiology and Disease
por: Duan, Cunming, et al.
Publicado: (2020)

Immune System Effects of Insulin-Like Peptide 5 in a Mouse Model
por: Vahkal, Brett, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_nop6iiuud8fuhl6d85m4oacvqj