Data on the effect of maternal separation coupled with social isolation in a forced swim test and gene expression of glial fibrillary acid protein in the prefrontal cortex of rats

Early life adversity, such as neglect, increases the risk for major depressive disorder and anxiety disorders. It is well-known that astrocytes have key roles in brain function. In this paper, we show the effect of maternal separation (MS) coupled with social isolation on stress response and gene ex...

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Detalles Bibliográficos
Autores principales: Yamawaki, Yosuke, Nishida, Misako, Harada, Kana, Akagi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Neurosciences   
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996303/
https://www.ncbi.nlm.nih.gov/pubmed/29900207
http://dx.doi.org/10.1016/j.dib.2018.03.055
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author Yamawaki, Yosuke
Nishida, Misako
Harada, Kana
Akagi, Hiroyuki
author_facet Yamawaki, Yosuke
Nishida, Misako
Harada, Kana
Akagi, Hiroyuki
author_sort Yamawaki, Yosuke
collection PubMed
description Early life adversity, such as neglect, increases the risk for major depressive disorder and anxiety disorders. It is well-known that astrocytes have key roles in brain function. In this paper, we show the effect of maternal separation (MS) coupled with social isolation on stress response and gene expression of glial fibrillary acidic protein (GFAP) as a marker of astrocytes, in early life and adulthood. Stress response was evaluated by using a forced swim test. GFAP gene expression level was evaluated by using the quantitative polymerase chain reaction (qPCR) method. The data in this article provide indexes affected by early life stress.
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spelling pubmed-59963032018-06-13 Data on the effect of maternal separation coupled with social isolation in a forced swim test and gene expression of glial fibrillary acid protein in the prefrontal cortex of rats Yamawaki, Yosuke Nishida, Misako Harada, Kana Akagi, Hiroyuki Data Brief Neurosciences    Early life adversity, such as neglect, increases the risk for major depressive disorder and anxiety disorders. It is well-known that astrocytes have key roles in brain function. In this paper, we show the effect of maternal separation (MS) coupled with social isolation on stress response and gene expression of glial fibrillary acidic protein (GFAP) as a marker of astrocytes, in early life and adulthood. Stress response was evaluated by using a forced swim test. GFAP gene expression level was evaluated by using the quantitative polymerase chain reaction (qPCR) method. The data in this article provide indexes affected by early life stress. Elsevier 2018-03-16 /pmc/articles/PMC5996303/ /pubmed/29900207 http://dx.doi.org/10.1016/j.dib.2018.03.055 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Neurosciences   
Yamawaki, Yosuke
Nishida, Misako
Harada, Kana
Akagi, Hiroyuki
Data on the effect of maternal separation coupled with social isolation in a forced swim test and gene expression of glial fibrillary acid protein in the prefrontal cortex of rats
title Data on the effect of maternal separation coupled with social isolation in a forced swim test and gene expression of glial fibrillary acid protein in the prefrontal cortex of rats
title_full Data on the effect of maternal separation coupled with social isolation in a forced swim test and gene expression of glial fibrillary acid protein in the prefrontal cortex of rats
title_fullStr Data on the effect of maternal separation coupled with social isolation in a forced swim test and gene expression of glial fibrillary acid protein in the prefrontal cortex of rats
title_full_unstemmed Data on the effect of maternal separation coupled with social isolation in a forced swim test and gene expression of glial fibrillary acid protein in the prefrontal cortex of rats
title_short Data on the effect of maternal separation coupled with social isolation in a forced swim test and gene expression of glial fibrillary acid protein in the prefrontal cortex of rats
title_sort data on the effect of maternal separation coupled with social isolation in a forced swim test and gene expression of glial fibrillary acid protein in the prefrontal cortex of rats
topic Neurosciences   
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996303/
https://www.ncbi.nlm.nih.gov/pubmed/29900207
http://dx.doi.org/10.1016/j.dib.2018.03.055
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