Total Syntheses of Bulgecins A, B, and C and Their Bactericidal Potentiation of the β-Lactam Antibiotics

[Image: see text] The bulgecins are iminosaccharide secondary metabolites of the Gram-negative bacterium Paraburkholderia acidophila and inhibitors of lytic transglycosylases of bacterial cell-wall biosynthesis and remodeling. The activities of the bulgecins are intimately intertwined with the mecha...

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Detalles Bibliográficos
Autores principales: Tomoshige, Shusuke, Dik, David A., Akabane-Nakata, Masaaki, Madukoma, Chinedu S., Fisher, Jed F., Shrout, Joshua D., Mobashery, Shahriar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996343/
https://www.ncbi.nlm.nih.gov/pubmed/29716193
http://dx.doi.org/10.1021/acsinfecdis.8b00105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996343/
https://www.ncbi.nlm.nih.gov/pubmed/29716193
http://dx.doi.org/10.1021/acsinfecdis.8b00105

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