An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles

The fundamental importance of membrane proteins in drug discovery has meant that membrane mimetic systems for studying membrane proteins are of increasing interest. One such system has been the amphipathic, negatively charged poly(styrene-co-maleic acid) (SMA) polymer to form “SMA Lipid Particles” (...

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Detalles Bibliográficos
Autores principales: Hall, Stephen C. L., Tognoloni, Cecilia, Charlton, Jack, Bragginton, Éilís C., Rothnie, Alice J., Sridhar, Pooja, Wheatley, Mark, Knowles, Timothy J., Arnold, Thomas, Edler, Karen J., Dafforn, Tim R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996351/
https://www.ncbi.nlm.nih.gov/pubmed/29845165
http://dx.doi.org/10.1039/c8nr01322e

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