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Image-guided chemotherapy with specifically tuned blood brain barrier permeability in glioma margins
Blood-brain barrier (BBB) disruption is frequently observed in the glioma region. However, the tumor uptake of drugs is still too low to meet the threshold of therapeutic purpose. Method: A tumor vasculature-targeted nanoagonist was developed. Glioma targeting specificity of the nanoagonist was eval...
Autores principales: | Gao, Xihui, Yue, Qi, Liu, Yikang, Fan, Dandan, Fan, Kun, Li, Sihan, Qian, Jun, Han, Limei, Fang, Fang, Xu, Fulin, Geng, Daoying, Chen, Liang, Zhou, Xin, Mao, Ying, Li, Cong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996359/ https://www.ncbi.nlm.nih.gov/pubmed/29896307 http://dx.doi.org/10.7150/thno.24784 |
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