PIAS3-mediated feedback loops promote chronic colitis-associated malignant transformation

Rationale: Colitis-associated colorectal cancer (CAC) usually exhibits an accelerated disease progression, an increased resistance to therapeutic drugs and a higher mortality rate than sporadic colorectal cancer (CRC). PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family; howev...

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Detalles Bibliográficos
Autores principales: Ma, Junting, Yang, Yaping, Fu, Yong, Guo, Feilong, Zhang, Xiaoyi, Xiao, Shuke, Zhu, Weiming, Huang, Zhen, Zhang, Junfeng, Chen, Jiangning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996365/
https://www.ncbi.nlm.nih.gov/pubmed/29896300
http://dx.doi.org/10.7150/thno.23046

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