miR-30 Family: A Promising Regulator in Development and Disease

MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate posttranscriptional expression of target genes. Accumulating evidences have demonstrated that the miR-30 family, as a member of microRNAs, played a crucial regulating role in the development of tissues and organs and the pathogenes...

Descripción completa

Detalles Bibliográficos
Autores principales: Mao, Ling, Liu, Shiming, Hu, Lin, Jia, Li, Wang, Hairong, Guo, Mengmeng, Chen, Chao, Liu, Yun, Xu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996469/
https://www.ncbi.nlm.nih.gov/pubmed/30003109
http://dx.doi.org/10.1155/2018/9623412
Descripción
Sumario:MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate posttranscriptional expression of target genes. Accumulating evidences have demonstrated that the miR-30 family, as a member of microRNAs, played a crucial regulating role in the development of tissues and organs and the pathogenesis of clinical diseases, which indicated that it may be a promising regulator in development and disease. This review aims to clarify the current progress on the regulating role of miR-30 family in tissues and organs development and related disease and highlight their research prospective in the future.

Ejemplares similares