miR-30 Family: A Promising Regulator in Development and Disease

MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate posttranscriptional expression of target genes. Accumulating evidences have demonstrated that the miR-30 family, as a member of microRNAs, played a crucial regulating role in the development of tissues and organs and the pathogenes...

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Detalles Bibliográficos
Autores principales: Mao, Ling, Liu, Shiming, Hu, Lin, Jia, Li, Wang, Hairong, Guo, Mengmeng, Chen, Chao, Liu, Yun, Xu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996469/
https://www.ncbi.nlm.nih.gov/pubmed/30003109
http://dx.doi.org/10.1155/2018/9623412
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author Mao, Ling
Liu, Shiming
Hu, Lin
Jia, Li
Wang, Hairong
Guo, Mengmeng
Chen, Chao
Liu, Yun
Xu, Lin
author_facet Mao, Ling
Liu, Shiming
Hu, Lin
Jia, Li
Wang, Hairong
Guo, Mengmeng
Chen, Chao
Liu, Yun
Xu, Lin
author_sort Mao, Ling
collection PubMed
description MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate posttranscriptional expression of target genes. Accumulating evidences have demonstrated that the miR-30 family, as a member of microRNAs, played a crucial regulating role in the development of tissues and organs and the pathogenesis of clinical diseases, which indicated that it may be a promising regulator in development and disease. This review aims to clarify the current progress on the regulating role of miR-30 family in tissues and organs development and related disease and highlight their research prospective in the future.
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spelling pubmed-59964692018-07-12 miR-30 Family: A Promising Regulator in Development and Disease Mao, Ling Liu, Shiming Hu, Lin Jia, Li Wang, Hairong Guo, Mengmeng Chen, Chao Liu, Yun Xu, Lin Biomed Res Int Review Article MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate posttranscriptional expression of target genes. Accumulating evidences have demonstrated that the miR-30 family, as a member of microRNAs, played a crucial regulating role in the development of tissues and organs and the pathogenesis of clinical diseases, which indicated that it may be a promising regulator in development and disease. This review aims to clarify the current progress on the regulating role of miR-30 family in tissues and organs development and related disease and highlight their research prospective in the future. Hindawi 2018-05-29 /pmc/articles/PMC5996469/ /pubmed/30003109 http://dx.doi.org/10.1155/2018/9623412 Text en Copyright © 2018 Ling Mao et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Mao, Ling
Liu, Shiming
Hu, Lin
Jia, Li
Wang, Hairong
Guo, Mengmeng
Chen, Chao
Liu, Yun
Xu, Lin
miR-30 Family: A Promising Regulator in Development and Disease
title miR-30 Family: A Promising Regulator in Development and Disease
title_full miR-30 Family: A Promising Regulator in Development and Disease
title_fullStr miR-30 Family: A Promising Regulator in Development and Disease
title_full_unstemmed miR-30 Family: A Promising Regulator in Development and Disease
title_short miR-30 Family: A Promising Regulator in Development and Disease
title_sort mir-30 family: a promising regulator in development and disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996469/
https://www.ncbi.nlm.nih.gov/pubmed/30003109
http://dx.doi.org/10.1155/2018/9623412
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