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The Antidiabetic Agent Sodium Tungstate Induces Abnormal Glycogen Accumulation in Renal Proximal Tubules from Diabetic IRS2-Knockout Mice
The kidney is an insulin-sensitive organ involved in glucose homeostasis. One major effect of insulin is to induce glycogen storage in the liver and muscle. However, no significant glycogen stores are detected in normal kidneys, but diabetic subjects present a characteristic renal histopathological...
Autores principales: | Bertinat, Romina, Westermeier, Francisco, Silva, Pamela, Gatica, Rodrigo, Oliveira, Joana Moitinho, Nualart, Francisco, Gomis, Ramón, Yáñez, Alejandro J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996472/ https://www.ncbi.nlm.nih.gov/pubmed/30003110 http://dx.doi.org/10.1155/2018/5697970 |
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