Cargando…
Identification of multiple proteoforms biomarkers on clinical samples by routine Top-Down approaches
Top-Down approaches have an extremely high biological relevance, especially when it comes to biomarker discovery, but the necessary pre-fractionation constraints are not easily compatible with the robustness requirements and the size of clinical sample cohorts. We have demonstrated that intact prote...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996497/ https://www.ncbi.nlm.nih.gov/pubmed/29900270 http://dx.doi.org/10.1016/j.dib.2018.03.114 |