Disseminated Multi-system Sarcoidosis Mimicking Metastases on (18)F-FDG PET/CT

A 60-year-old female with no significant medical history presented with hematuria. A computed tomography (CT) scan revealed extensive lymphadenopathy with hypodensities in the liver and spleen, and she was referred for an (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/CT (PET/CT)...

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Detalles Bibliográficos
Autores principales: Makis, William, Palayew, Mark, Rush, Christopher, Probst, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2018
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996599/
https://www.ncbi.nlm.nih.gov/pubmed/29889033
http://dx.doi.org/10.4274/mirt.29200
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author Makis, William
Palayew, Mark
Rush, Christopher
Probst, Stephan
author_facet Makis, William
Palayew, Mark
Rush, Christopher
Probst, Stephan
author_sort Makis, William
collection PubMed
description A 60-year-old female with no significant medical history presented with hematuria. A computed tomography (CT) scan revealed extensive lymphadenopathy with hypodensities in the liver and spleen, and she was referred for an (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/CT (PET/CT) study to assess for malignancy of unknown primary. PET/CT revealed extensive (18)F-FDG avid lymphadenopathy as well as innumerable intensely (18)F-FDG avid lung, liver and splenic nodules, highly concerning for malignancy. A PET-guided bone marrow biopsy of the posterior superior iliac spine revealed several non-necrotizing, well-formed granulomas, consistent with sarcoidosis. The patient was managed conservatively and remained clinically well over the subsequent 9 years of follow-up.
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spelling pubmed-59965992018-06-14 Disseminated Multi-system Sarcoidosis Mimicking Metastases on (18)F-FDG PET/CT Makis, William Palayew, Mark Rush, Christopher Probst, Stephan Mol Imaging Radionucl Ther Interesting Image A 60-year-old female with no significant medical history presented with hematuria. A computed tomography (CT) scan revealed extensive lymphadenopathy with hypodensities in the liver and spleen, and she was referred for an (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/CT (PET/CT) study to assess for malignancy of unknown primary. PET/CT revealed extensive (18)F-FDG avid lymphadenopathy as well as innumerable intensely (18)F-FDG avid lung, liver and splenic nodules, highly concerning for malignancy. A PET-guided bone marrow biopsy of the posterior superior iliac spine revealed several non-necrotizing, well-formed granulomas, consistent with sarcoidosis. The patient was managed conservatively and remained clinically well over the subsequent 9 years of follow-up. Galenos Publishing 2018-06 2018-06-07 /pmc/articles/PMC5996599/ /pubmed/29889033 http://dx.doi.org/10.4274/mirt.29200 Text en ©Copyright 2018 by Turkish Society of Nuclear Medicine / Molecular Imaging and Radionuclide Therapy published by Galenos Yayinevi. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Interesting Image
Makis, William
Palayew, Mark
Rush, Christopher
Probst, Stephan
Disseminated Multi-system Sarcoidosis Mimicking Metastases on (18)F-FDG PET/CT
title Disseminated Multi-system Sarcoidosis Mimicking Metastases on (18)F-FDG PET/CT
title_full Disseminated Multi-system Sarcoidosis Mimicking Metastases on (18)F-FDG PET/CT
title_fullStr Disseminated Multi-system Sarcoidosis Mimicking Metastases on (18)F-FDG PET/CT
title_full_unstemmed Disseminated Multi-system Sarcoidosis Mimicking Metastases on (18)F-FDG PET/CT
title_short Disseminated Multi-system Sarcoidosis Mimicking Metastases on (18)F-FDG PET/CT
title_sort disseminated multi-system sarcoidosis mimicking metastases on (18)f-fdg pet/ct
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996599/
https://www.ncbi.nlm.nih.gov/pubmed/29889033
http://dx.doi.org/10.4274/mirt.29200
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