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Data on the effect of knockout of neruregulin-1 type III on Remak bundle structure
Schwann cells in the peripheral nervous system wrap around large diameter axons to form the myelin sheath, that contains one axon. Schwann cells also wrap around small diameter axons to form the Remak bundle, that contains many axons. Neuregulin-1 (NRG1) type III binds Schwann cell plasma membrane E...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996742/ https://www.ncbi.nlm.nih.gov/pubmed/29900241 http://dx.doi.org/10.1016/j.dib.2018.03.099 |
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author | Miyamoto, Yuki Torii, Tomohiro Inoue, Masashi Morimoto, Takako Yamamoto, Masahiro Yamauchi, Junji |
author_facet | Miyamoto, Yuki Torii, Tomohiro Inoue, Masashi Morimoto, Takako Yamamoto, Masahiro Yamauchi, Junji |
author_sort | Miyamoto, Yuki |
collection | PubMed |
description | Schwann cells in the peripheral nervous system wrap around large diameter axons to form the myelin sheath, that contains one axon. Schwann cells also wrap around small diameter axons to form the Remak bundle, that contains many axons. Neuregulin-1 (NRG1) type III binds Schwann cell plasma membrane ErbB2/3 receptor to regulate morphological changes of Schwann cells. Herein we provide the data on the effect of NRG1 type III knockout (Miyamoto et al., 2017) [1] on the Remak bundle structure. Since complete knockout mice of NRG1type III are embryonically lethal, we have usedNRG1type III (+/−) mice's sciatic nerves in these experiments. |
format | Online Article Text |
id | pubmed-5996742 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-59967422018-06-13 Data on the effect of knockout of neruregulin-1 type III on Remak bundle structure Miyamoto, Yuki Torii, Tomohiro Inoue, Masashi Morimoto, Takako Yamamoto, Masahiro Yamauchi, Junji Data Brief Neurosciences Schwann cells in the peripheral nervous system wrap around large diameter axons to form the myelin sheath, that contains one axon. Schwann cells also wrap around small diameter axons to form the Remak bundle, that contains many axons. Neuregulin-1 (NRG1) type III binds Schwann cell plasma membrane ErbB2/3 receptor to regulate morphological changes of Schwann cells. Herein we provide the data on the effect of NRG1 type III knockout (Miyamoto et al., 2017) [1] on the Remak bundle structure. Since complete knockout mice of NRG1type III are embryonically lethal, we have usedNRG1type III (+/−) mice's sciatic nerves in these experiments. Elsevier 2018-03-27 /pmc/articles/PMC5996742/ /pubmed/29900241 http://dx.doi.org/10.1016/j.dib.2018.03.099 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Neurosciences Miyamoto, Yuki Torii, Tomohiro Inoue, Masashi Morimoto, Takako Yamamoto, Masahiro Yamauchi, Junji Data on the effect of knockout of neruregulin-1 type III on Remak bundle structure |
title | Data on the effect of knockout of neruregulin-1 type III on Remak bundle structure |
title_full | Data on the effect of knockout of neruregulin-1 type III on Remak bundle structure |
title_fullStr | Data on the effect of knockout of neruregulin-1 type III on Remak bundle structure |
title_full_unstemmed | Data on the effect of knockout of neruregulin-1 type III on Remak bundle structure |
title_short | Data on the effect of knockout of neruregulin-1 type III on Remak bundle structure |
title_sort | data on the effect of knockout of neruregulin-1 type iii on remak bundle structure |
topic | Neurosciences |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996742/ https://www.ncbi.nlm.nih.gov/pubmed/29900241 http://dx.doi.org/10.1016/j.dib.2018.03.099 |
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