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Data on whole length myosin binding protein C stabilizes myosin S2 as measured by gravitational force spectroscopy
Data presented in this article relates to the research article entitled “Whole length myosin binding protein C stabilizes myosin subfragment-2 (S2) flexibility as measured by gravitational force spectroscopy.” (Singh et al., 2018) [1]. The data exhibits the purified skeletal myosin binding protein C...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996744/ https://www.ncbi.nlm.nih.gov/pubmed/29900280 http://dx.doi.org/10.1016/j.dib.2018.04.002 |
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author | Singh, Rohit R. Dunn, James W. Qadan, Motamed M. Hall, Nakiuda Wang, Kathy K. Root, Douglas D. |
author_facet | Singh, Rohit R. Dunn, James W. Qadan, Motamed M. Hall, Nakiuda Wang, Kathy K. Root, Douglas D. |
author_sort | Singh, Rohit R. |
collection | PubMed |
description | Data presented in this article relates to the research article entitled “Whole length myosin binding protein C stabilizes myosin subfragment-2 (S2) flexibility as measured by gravitational force spectroscopy.” (Singh et al., 2018) [1]. The data exhibits the purified skeletal myosin binding protein C (MyBPC) from rabbit back muscle was of slow skeletal type confirmed by chromatography and in unphosphorylated state based on its isoelectric point (pI) by chromatofocussing. The competitive enzyme linked immunosorbent assay (cELISA) data displayed the site specificity of polyclonal anti-S2 antibody to myosin S2. This polyclonal antibody binding site corresponds to a familial hypertrophic cardiomyopathy (FHC) point mutation hotspot on myosin S2 illustrated in a figure of compiled data. |
format | Online Article Text |
id | pubmed-5996744 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-59967442018-06-13 Data on whole length myosin binding protein C stabilizes myosin S2 as measured by gravitational force spectroscopy Singh, Rohit R. Dunn, James W. Qadan, Motamed M. Hall, Nakiuda Wang, Kathy K. Root, Douglas D. Data Brief Proteomics and Biochemistry Data presented in this article relates to the research article entitled “Whole length myosin binding protein C stabilizes myosin subfragment-2 (S2) flexibility as measured by gravitational force spectroscopy.” (Singh et al., 2018) [1]. The data exhibits the purified skeletal myosin binding protein C (MyBPC) from rabbit back muscle was of slow skeletal type confirmed by chromatography and in unphosphorylated state based on its isoelectric point (pI) by chromatofocussing. The competitive enzyme linked immunosorbent assay (cELISA) data displayed the site specificity of polyclonal anti-S2 antibody to myosin S2. This polyclonal antibody binding site corresponds to a familial hypertrophic cardiomyopathy (FHC) point mutation hotspot on myosin S2 illustrated in a figure of compiled data. Elsevier 2018-04-05 /pmc/articles/PMC5996744/ /pubmed/29900280 http://dx.doi.org/10.1016/j.dib.2018.04.002 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Proteomics and Biochemistry Singh, Rohit R. Dunn, James W. Qadan, Motamed M. Hall, Nakiuda Wang, Kathy K. Root, Douglas D. Data on whole length myosin binding protein C stabilizes myosin S2 as measured by gravitational force spectroscopy |
title | Data on whole length myosin binding protein C stabilizes myosin S2 as measured by gravitational force spectroscopy |
title_full | Data on whole length myosin binding protein C stabilizes myosin S2 as measured by gravitational force spectroscopy |
title_fullStr | Data on whole length myosin binding protein C stabilizes myosin S2 as measured by gravitational force spectroscopy |
title_full_unstemmed | Data on whole length myosin binding protein C stabilizes myosin S2 as measured by gravitational force spectroscopy |
title_short | Data on whole length myosin binding protein C stabilizes myosin S2 as measured by gravitational force spectroscopy |
title_sort | data on whole length myosin binding protein c stabilizes myosin s2 as measured by gravitational force spectroscopy |
topic | Proteomics and Biochemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996744/ https://www.ncbi.nlm.nih.gov/pubmed/29900280 http://dx.doi.org/10.1016/j.dib.2018.04.002 |
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