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Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived schwann cells

Neurofibromatosis type I (NF1) is an autosomal dominant genetic condition characterized by peripheral nervous system tumors (PNSTs), including plexiform neurofibromas (pNFs) that cause nerve dysfunction, deformity, pain damage to adjacent structures, and can undergo malignant transformation. There a...

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Detalles Bibliográficos
Autores principales: Ferrer, Marc, Gosline, Sara J. C., Stathis, Marigo, Zhang, Xiaohu, Guo, Xindi, Guha, Rajarshi, Ryman, Dannielle A., Wallace, Margaret R., Kasch-Semenza, Laura, Hao, Haiping, Ingersoll, Roxann, Mohr, David, Thomas, Craig, Verma, Sharad, Guinney, Justin, Blakeley, Jaishri O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996849/
https://www.ncbi.nlm.nih.gov/pubmed/29893754
http://dx.doi.org/10.1038/sdata.2018.106