Modeling Chronic Toxicity: A Comparison of Experimental Variability With (Q)SAR/Read-Across Predictions

This study compares the accuracy of (Q)SAR/read-across predictions with the experimental variability of chronic lowest-observed-adverse-effect levels (LOAELs) from in vivo experiments. We could demonstrate that predictions of the lazy structure-activity relationships (lazar) algorithm within the app...

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Detalles Bibliográficos
Autores principales: Helma, Christoph, Vorgrimmler, David, Gebele, Denis, Gütlein, Martin, Engeli, Barbara, Zarn, Jürg, Schilter, Benoit, Lo Piparo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996880/
https://www.ncbi.nlm.nih.gov/pubmed/29922154
http://dx.doi.org/10.3389/fphar.2018.00413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996880/
https://www.ncbi.nlm.nih.gov/pubmed/29922154
http://dx.doi.org/10.3389/fphar.2018.00413

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