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Egr-1 mediates leptin-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells

Loss of peroxisome proliferator-activated receptor γ (PPARγ) has been found to contribute to pulmonary artery smooth muscle cell (PASMC) proliferation and pulmonary arterial remodeling therefore the development of pulmonary hypertension (PH). Yet, the molecular mechanisms underlying PPARγ reduction...

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Detalles Bibliográficos
Autores principales:	Xie, Xinming, Li, Shaojun, Zhu, Yanting, Liu, Lu, Ke, Rui, Wang, Jian, Yan, Xin, Yang, Lan, Gao, Li, Zang, Weijin, Li, Manxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996952/ https://www.ncbi.nlm.nih.gov/pubmed/29212876 http://dx.doi.org/10.1091/mbc.E17-03-0141

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