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IMiQ: a novel protein quality control compartment protecting mitochondrial functional integrity
Aggregation processes can cause severe perturbations of cellular homeostasis and are frequently associated with diseases. We performed a comprehensive analysis of mitochondrial quality and function in the presence of aggregation-prone polypeptides. Despite a significant aggregate formation inside mi...
Autores principales: | Bruderek, Michael, Jaworek, Witold, Wilkening, Anne, Rüb, Cornelia, Cenini, Giovanna, Förtsch, Arion, Sylvester, Marc, Voos, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996957/ https://www.ncbi.nlm.nih.gov/pubmed/29212875 http://dx.doi.org/10.1091/mbc.E17-01-0027 |
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